서울아산병원 이비인후과 장용주 교수를 교신저자로 하여 저술한 “Usefulness of Septodermoplasty in Hereditary Hemorrhagic Telangiectasia.” 라는 논문이 Korean J Otorhinolaryngol-Head Neck Surg  2015년 개재되었으며 유전성 출혈성 모세혈관 확장증 관련 2800여회 넘게 인용되었다.

ABSTRACT

BACKGROUND AND OBJECTIVES:

Epistaxis is the most common symptom in patients with hereditary hemorrhagic telangiectasia (HHT). The aim of this study is to report treatment of severe epistaxis related to HHT with the septodermoplasty and to assess patient outcomes.

SUBJECTS AND METHOD:

Six patients with HHT who underwent septodermoplasty from 2009 to 2013 were reviewed retrospectively. We analyzed the clinical characteristics, surgical management and treatment outcomes.

RESULTS:

Three patients had been diagnosed with definite HHT and three patients with possible HHT. Three patients had combined abnormal vascular structures in visceral organs. The mean preoperative and postoperative hemoglobin were 7.2 g/dL and 12.8 g/dL, respectively, and visual analogue scale score for frequency and intensity of nasal bleeding remarkably decreased after septodermoplasty in all patients.

CONCLUSION:

Septodermoplasty was a safe and efficacious procedure for reducing the frequency and severity of bleeding in most patients with intractable epistaxis and HHT.